Biography
Professor Mobashery was an undergraduate at the University of Southern California. Subsequently he received his Ph.D. in chemistry from the University of Chicago in 1985. He carried out postdoctoral research from 1986 to 1988 at the Rockefeller University as a National Institute of Health Fellow. He joined the faculty at Wayne State University in 1989, where he went up the ranks to Professor by 1997. Professor Mobashery joined the faculty at Notre Dame in 2003 as the Navari Family Professor in Life Sciences.
Research Interests
The research interests of this laboratory center on bioorganic chemistry, organic synthesis, protein chemistry, enzymology and computational sciences. The research carried out in the laboratory employs a multidisciplinary approach to solve problems at the interface of chemistry and biology. Biologically active molecules are designed and synthesized in the laboratory to test important concepts in the mechanisms of action of antibiotics and enzyme inhibitors as potential pharmaceutical agents.
The research interests in the group encompass studies of mechanisms of resistance to antibiotics and the means to circumvent them, development of novel antibiotics, studies of the mechanism of action of these antibiotics and investigations of complex microbial systems such as the outer membrane and the cell wall. In non-microbial systems, the group is also interested in the molecular mechanisms of cancer metastasis and its intervention.
Recent Papers
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Contact Information
- Professor
- Office: 423 NSH
- Phone: 574.631.2933
- Contact by Email
Primary Research Areas
Research Specialties
- Drug Design & Discovery
- Structural Biology
- Synthetic Chemistry
- Theoretical & Computational Chemistry
- Biophysics
