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fig11.jpg

Three dimensional structure of tumor antigen and cancer vaccine candiate

This figure shows the three-dimensional structure of a a major tumor rejection antigen and a cancer vaccine candidate bound to the class I MHC protein HLA-A2. Panel A shows the overall architecture of the peptide/protein complex, and Panel B shows the electron density and conformations of the tumor antigen (A) and vaccine candidate (B).

See Borbulevych et al., Journal of Immunology 174, p. 4812 (2005).

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